{"id":8737,"date":"2025-05-15T17:43:30","date_gmt":"2025-05-15T08:43:30","guid":{"rendered":"https:\/\/kenkoubyouki.com\/?p=8737"},"modified":"2025-05-15T17:43:30","modified_gmt":"2025-05-15T08:43:30","slug":"post-8737","status":"publish","type":"post","link":"https:\/\/kenkoubyouki.com\/?p=8737","title":{"rendered":"1\u56de\u3084\u308b\u3068\u899a\u9192\u5264\u304b\u3089\u629c\u3051\u51fa\u305b\u306a\u304f\u306a\u308b\u539f\u7406\u3002\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u793a\u3057\u307e\u3059"},"content":{"rendered":"

\u899a\u9192\u5264\uff08\u4e00\u822c\u7684\u306b\u30e1\u30bf\u30f3\u30d5\u30a7\u30bf\u30df\u30f3\u306a\u3069\u3092\u6307\u3057\u307e\u3059\uff09\u306f\u3001\u4e00\u5ea6\u306e\u4f7f\u7528\u3067\u5f37\u3044\u4f9d\u5b58\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u85ac\u7269\u3067\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u305d\u306e\u300c\u4e00\u56de\u3067\u629c\u3051\u51fa\u305b\u306a\u304f\u306a\u308b\u300d\u3068\u8a00\u308f\u308c\u308b\u73fe\u8c61\u306b\u3064\u3044\u3066\u3001\u8133\u306e\u795e\u7d4c\u79d1\u5b66\u7684\u306a\u89b3\u70b9\u3001\u5fc3\u7406\u7684\u8981\u56e0\u3001\u793e\u4f1a\u7684\u5f71\u97ff\u3092\u542b\u3081\u3066\u89e3\u8aac\u3057\u3001\u79d1\u5b66\u7684\u6839\u62e0\uff08\u30a8\u30d3\u30c7\u30f3\u30b9\uff09\u3082\u4ea4\u3048\u3066\u7d044000\u6587\u5b57\u3067\u8aac\u660e\u3057\u307e\u3059\u3002<\/span><\/p>\n

\n

\u4e00\u5ea6\u306e\u4f7f\u7528\u3067\u899a\u9192\u5264\u4f9d\u5b58\u304c\u59cb\u307e\u308b\u7406\u7531\u3068\u79d1\u5b66\u7684\u6839\u62e0<\/span><\/h2>\n

1. \u30c9\u30d1\u30df\u30f3\u5206\u6ccc\u306e\u7570\u5e38\u306a\u5897\u52a0<\/span><\/h3>\n

\u899a\u9192\u5264\u3092\u4f7f\u7528\u3059\u308b\u3068\u3001\u8133\u5185\u3067\u300c\u5feb\u697d\u30db\u30eb\u30e2\u30f3\u300d\u3068\u3082\u547c\u3070\u308c\u308b\u30c9\u30d1\u30df\u30f3<\/strong>\u306e\u653e\u51fa\u304c\u7570\u5e38\u306a\u30ec\u30d9\u30eb\u306b\u307e\u3067\u5897\u52a0\u3057\u307e\u3059\u3002\u30e1\u30bf\u30f3\u30d5\u30a7\u30bf\u30df\u30f3\u306e\u5834\u5408\u3001\u901a\u5e38\u306e10\u500d\u4ee5\u4e0a<\/strong>\u306e\u30c9\u30d1\u30df\u30f3\u304c\u6025\u6fc0\u306b\u653e\u51fa\u3055\u308c\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08Volkow et al., 2001\uff09\u3002<\/span><\/p>\n

\u3053\u306e\u5f37\u70c8\u306a\u5feb\u611f\u306f\u3001\u8133\u306e\u300c\u5831\u916c\u7cfb\u300d\uff08\u3068\u304f\u306b\u5074\u5750\u6838\u3084\u8179\u5074\u88ab\u84cb\u91ce\uff09\u3092\u523a\u6fc0\u3057\u3001\u5feb\u697d\u8a18\u61b6\uff08\u5831\u916c\u8a18\u61b6\uff09\u3068\u3057\u3066\u5f37\u304f\u523b\u307f\u8fbc\u307e\u308c\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u751f\u304d\u6b8b\u308b\u305f\u3081\u306b\u91cd\u8981\u306a\u884c\u52d5\uff08\u4f8b\uff1a\u98df\u4e8b\u3001\u6027\u4ea4\u306a\u3069\uff09\u3092\u5f37\u5316\u3059\u308b\u672c\u6765\u306e\u4ed5\u7d44\u307f\u3067\u3059\u304c\u3001\u899a\u9192\u5264\u306f\u3053\u306e\u4ed5\u7d44\u307f\u3092\u4eba\u5de5\u7684\u304b\u3064\u5f37\u70c8\u306b\u30cf\u30a4\u30b8\u30e3\u30c3\u30af<\/strong>\u3057\u307e\u3059\u3002<\/span><\/p>\n

\u53c2\u8003\u6587\u732e\uff1a<\/span><\/h4>\n
    \n
  • \n

    Volkow, N.D. et al. (2001). Mechanism of Action of Methamphetamine<\/em>. JAMA Psychiatry<\/em>.<\/span><\/p>\n<\/li>\n<\/ul>\n

    \n

    2. \u4e00\u56de\u306e\u4f7f\u7528\u3067\u795e\u7d4c\u56de\u8def\u306b\u300c\u75d5\u8de1\u300d\u304c\u6b8b\u308b<\/span><\/h3>\n

    \u52d5\u7269\u5b9f\u9a13\u3084\u8133\u753b\u50cf\u7814\u7a76\u306b\u3088\u308a\u3001\u4e00\u5ea6\u306e\u4f7f\u7528\u3067\u3082\u795e\u7d4c\u7d30\u80de\u9593\u306e\u30b7\u30ca\u30d7\u30b9\u69cb\u9020\u304c\u5909\u5316<\/strong>\u3057\u3001\u305d\u308c\u304c\u6570\u9031\u9593\u304b\u3089\u6570\u30f6\u6708\u4ee5\u4e0a\u6301\u7d9a\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08Robinson & Kolb, 2004\uff09\u3002\u3053\u308c\u3092\u300c\u611f\u4f5c\uff08sensitization\uff09<\/strong>\u300d\u3068\u547c\u3073\u3001\u518d\u4f7f\u7528\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u8981\u56e0\u3067\u3059\u3002<\/span><\/p>\n

    \u3053\u306e\u795e\u7d4c\u53ef\u5851\u6027\u306e\u5909\u5316\u306b\u3088\u308a\u3001\u4f7f\u7528\u8005\u306f\u300c\u307e\u305f\u3042\u306e\u5feb\u611f\u3092\u5473\u308f\u3044\u305f\u3044\u300d\u3068\u3044\u3046**\u5f37\u3044\u6b32\u6c42\uff08\u6e07\u671b\uff1d\u30af\u30ec\u30fc\u30d3\u30f3\u30b0\uff09**\u3092\u62b1\u304f\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u300c\u4e00\u56de\u3067\u7d42\u308f\u308b\u300d\u3053\u3068\u304c\u975e\u5e38\u306b\u56f0\u96e3\u306b\u306a\u308b\u306e\u3067\u3059\u3002<\/span><\/p>\n

    \u53c2\u8003\u6587\u732e\uff1a<\/span><\/h4>\n
      \n
    • \n

      Robinson, T.E. & Kolb, B. (2004). Structural plasticity associated with exposure to drugs of abuse<\/em>. Neuropharmacology<\/em>.<\/span><\/p>\n<\/li>\n<\/ul>\n

      \n

      3. \u81ea\u5236\u5fc3\u3092\u3064\u304b\u3055\u3069\u308b\u524d\u982d\u524d\u76ae\u8cea\u306e\u6a5f\u80fd\u4f4e\u4e0b<\/span><\/h3>\n

      \u899a\u9192\u5264\u306f\u3001\u601d\u8003\u30fb\u5224\u65ad\u30fb\u81ea\u5236\u306b\u95a2\u4e0e\u3059\u308b**\u524d\u982d\u524d\u76ae\u8cea\uff08prefrontal cortex\uff09**\u306e\u50cd\u304d\u3092\u5f31\u3081\u307e\u3059\u3002\u3053\u308c\u306f\u6162\u6027\u7684\u306a\u4f7f\u7528\u3067\u9855\u8457\u3067\u3059\u304c\u3001\u305f\u3063\u305f\u4e00\u5ea6\u306e\u4f7f\u7528\u3067\u3082\u4e00\u6642\u7684\u306a\u6a5f\u80fd\u4f4e\u4e0b<\/strong>\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08Goldstein & Volkow, 2002\uff09\u3002<\/span><\/p>\n

      \u3053\u306e\u7d50\u679c\u3001\u81ea\u5df1\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u80fd\u529b\u304c\u4e0b\u304c\u308a\u3001\u300c\u3084\u3081\u3088\u3046\u300d\u3068\u3044\u3046\u5224\u65ad\u304c\u50cd\u304d\u306b\u304f\u304f\u306a\u308a\u307e\u3059\u3002\u52a0\u3048\u3066\u3001\u300c\u81ea\u5206\u3060\u3051\u306f\u5927\u4e08\u592b\u300d\u300c\u3082\u3046\u4e00\u56de\u3060\u3051\u306a\u3089\u3044\u3044\u300d\u3068\u3044\u3046\u8a8d\u77e5\u306e\u3086\u304c\u307f<\/strong>\u304c\u5f37\u5316\u3055\u308c\u3001\u518d\u4f7f\u7528\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/span><\/p>\n

      \u53c2\u8003\u6587\u732e\uff1a<\/span><\/h4>\n
        \n
      • \n

        Goldstein, R.Z., & Volkow, N.D. (2002). Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex<\/em>. American Journal of Psychiatry<\/em>.<\/span><\/p>\n<\/li>\n<\/ul>\n

        \n

        4. \u5fc3\u7406\u7684\u4f9d\u5b58\u3068\u6761\u4ef6\u3065\u3051<\/span><\/h3>\n

        \u899a\u9192\u5264\u306e\u4f7f\u7528\u306b\u3088\u308a\u5f97\u3089\u308c\u308b\u5feb\u611f\u306f\u3001\u4f7f\u7528\u72b6\u6cc1\u3084\u74b0\u5883\uff08\u4f8b\uff1a\u5834\u6240\u3001\u97f3\u697d\u3001\u4eba\uff09\u3068\u5f37\u304f\u7d50\u3073\u3064\u304d\u307e\u3059\u3002\u3053\u308c\u3092\u53e4\u5178\u7684\u6761\u4ef6\u3065\u3051<\/strong>\u3068\u547c\u3073\u307e\u3059\uff08Pavlov\u306e\u72ac\u306e\u7406\u8ad6\u304c\u6709\u540d\u3067\u3059\uff09\u3002<\/span><\/p>\n

        \u305f\u3068\u3048\u3070\u3001\u4e00\u56de\u4f7f\u7528\u3057\u305f\u6642\u306e\u5834\u6240\u3084\u72b6\u6cc1\u3092\u518d\u3073\u7d4c\u9a13\u3059\u308b\u3068\u3001\u8133\u304c\u7121\u610f\u8b58\u306b\u300c\u899a\u9192\u5264\u3092\u6b32\u3059\u308b\u300d\u72b6\u614b\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u5b9f\u969b\u306b\u85ac\u3092\u6442\u53d6\u3057\u3066\u3044\u306a\u304f\u3066\u3082\u3001**\u5f37\u70c8\u306a\u518d\u4f7f\u7528\u6b32\u6c42\uff08\u30af\u30ec\u30fc\u30d3\u30f3\u30b0\uff09**\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/span><\/p>\n

        \n

        5. \u793e\u4f1a\u7684\u30fb\u5fc3\u7406\u7684\u80cc\u666f\u304c\u518d\u4f7f\u7528\u3092\u5f8c\u62bc\u3057\u3059\u308b<\/span><\/h3>\n

        \u4e00\u5ea6\u3067\u3082\u4f7f\u7528\u3059\u308b\u3068\u3001\u81ea\u5df1\u80af\u5b9a\u611f\u306e\u4f4e\u4e0b\u3084\u7f6a\u60aa\u611f\u3001\u5b64\u7acb\u611f\u3092\u62b1\u304f\u4eba\u304c\u591a\u304f\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u611f\u60c5\u306f\u30b9\u30c8\u30ec\u30b9\u306e\u30c8\u30ea\u30ac\u30fc\u3068\u306a\u308a\u3001\u300c\u9003\u907f\u300d\u3084\u300c\u73fe\u5b9f\u304b\u3089\u306e\u56de\u907f\u300d\u3068\u3057\u3066\u518d\u3073\u899a\u9192\u5264\u306b\u983c\u3063\u3066\u3057\u307e\u3046\u60aa\u5faa\u74b0\u304c\u751f\u307e\u308c\u307e\u3059\u3002<\/span><\/p>\n

        \u307e\u305f\u3001\u65e5\u672c\u3067\u306f\u899a\u9192\u5264\u4f7f\u7528\u6b74\u304c\u3042\u308b\u3053\u3068\u3067\u3001\u793e\u4f1a\u5fa9\u5e30\u304c\u56f0\u96e3\u306b\u306a\u308b\u3053\u3068\u3082\u591a\u304f\u3001\u5b64\u7acb\u2192\u30b9\u30c8\u30ec\u30b9\u2192\u518d\u4f7f\u7528<\/strong>\u3068\u3044\u3046\u30eb\u30fc\u30d7\u306b\u306f\u307e\u308a\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/span><\/p>\n

        \n

        6. \u5b9f\u969b\u306e\u8abf\u67fb\u7d50\u679c\uff08\u65e5\u672c\u56fd\u5185\uff09<\/span><\/h3>\n

        \u65e5\u672c\u306e\u6cd5\u52d9\u7701\u3084\u539a\u751f\u52b4\u50cd\u7701\u306e\u5831\u544a\u3067\u306f\u3001\u521d\u56de\u4f7f\u7528\u5f8c\u306e\u518d\u4f7f\u7528\u7387\u304c\u975e\u5e38\u306b\u9ad8\u304f<\/strong>\u3001\u899a\u9192\u5264\u4f7f\u7528\u7d4c\u9a13\u8005\u306e\u591a\u304f\u304c\u6570\u65e5\uff5e\u6570\u30f6\u6708\u4ee5\u5185\u306b2\u56de\u76ee\u3092\u4f7f\u7528<\/strong>\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n

        \u307e\u305f\u3001\u518d\u72af\u7387\u3082\u975e\u5e38\u306b\u9ad8\u304f\u3001\u899a\u9192\u5264\u53d6\u7de0\u6cd5\u9055\u53cd\u3067\u6709\u7f6a\u3068\u306a\u3063\u305f\u4eba\u306e\u7d0460\u301c70%\u304c5\u5e74\u4ee5\u5185\u306b\u518d\u72af<\/strong>\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u5358\u306a\u308b\u610f\u5fd7\u306e\u5f31\u3055\u3067\u306f\u306a\u304f\u3001\u4f9d\u5b58\u6027\u306e\u5f37\u3055\u3068\u793e\u4f1a\u7684\u652f\u63f4\u306e\u4e0d\u8db3<\/strong>\u304c\u5927\u304d\u304f\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n

        \u53c2\u8003\u8cc7\u6599\uff1a<\/span><\/h4>\n
          \n
        • \n

          \u539a\u751f\u52b4\u50cd\u7701\u300c\u85ac\u7269\u4e71\u7528\u5bfe\u7b56\u5e74\u6b21\u5831\u544a\u66f8\u300d<\/span><\/p>\n<\/li>\n

        • \n

          \u6cd5\u52d9\u7701\u300c\u518d\u72af\u9632\u6b62\u63a8\u9032\u8a08\u753b\u300d<\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          \u7d50\u8ad6\uff1a\u4e00\u56de\u306e\u4f7f\u7528\u3067\u3082\u300c\u623b\u308c\u306a\u304f\u306a\u308b\u300d\u7406\u7531<\/span><\/h3>\n

          \u4ee5\u4e0a\u306e\u3088\u3046\u306b\u3001\u899a\u9192\u5264\u306f\u305f\u3063\u305f\u4e00\u56de\u306e\u4f7f\u7528\u3067\u3082\u3001\u4ee5\u4e0b\u306e\u8981\u56e0\u306b\u3088\u3063\u3066\u629c\u3051\u51fa\u3057\u306b\u304f\u3044\u72b6\u614b\u306b\u9665\u308a\u307e\u3059\u3002<\/span><\/p>\n

            \n
          • \n

            \u8133\u5185\u30c9\u30d1\u30df\u30f3\u306e\u904e\u5270\u653e\u51fa<\/strong>\u306b\u3088\u308b\u7570\u5e38\u306a\u5feb\u697d\u4f53\u9a13<\/span><\/p>\n<\/li>\n

          • \n

            \u795e\u7d4c\u56de\u8def\u306e\u5909\u5316<\/strong>\uff08\u611f\u4f5c\u30fb\u53ef\u5851\u6027\uff09<\/span><\/p>\n<\/li>\n

          • \n

            \u81ea\u5236\u5fc3\u3092\u5f31\u3081\u308b\u8133\u306e\u524d\u982d\u524d\u76ae\u8cea\u306e\u6291\u5236<\/strong><\/span><\/p>\n<\/li>\n

          • \n

            \u74b0\u5883\u3068\u306e\u6761\u4ef6\u3065\u3051<\/strong>\u306b\u3088\u308b\u5f37\u3044\u518d\u4f7f\u7528\u6b32\u6c42<\/span><\/p>\n<\/li>\n

          • \n

            \u793e\u4f1a\u7684\u5b64\u7acb\u3084\u5fc3\u7406\u7684\u30b9\u30c8\u30ec\u30b9<\/strong>\u306b\u3088\u308b\u60aa\u5faa\u74b0<\/span><\/p>\n<\/li>\n<\/ul>\n

            \u305d\u306e\u305f\u3081\u3001\u899a\u9192\u5264\u306f\u300c\u4e00\u5ea6\u3060\u3051\u306a\u3089\u5927\u4e08\u592b\u300d\u3068\u3044\u3046\u8003\u3048\u304c\u6700\u3082\u5371\u967a\u3067\u3042\u308a\u3001\u4e00\u56de\u3067\u4eba\u751f\u304c\u5927\u304d\u304f\u5909\u308f\u3063\u3066\u3057\u307e\u3046\u30ea\u30b9\u30af<\/strong>\u3092\u4f34\u3046\u85ac\u7269\u3067\u3042\u308b\u3068\u8a00\u3048\u308b\u306e\u3067\u3059\u3002<\/span><\/p>\n

            \n

            \u88dc\u8db3\uff1a\u4f9d\u5b58\u304b\u3089\u306e\u56de\u5fa9\u3082\u53ef\u80fd<\/span><\/h3>\n

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